Acute pancreatitis, a potentially fatal inflammatory condition, necessitates effective management to minimize mortality and morbidity. Regional variations in incidence and the evolving landscape of guidelines underscore the need for regular audits. This study aimed to re-evaluate the management and outcomes of acute pancreatitis patients at Cumberland Infirmary in 2022, aligning with NICE guidelines and comparing results with the prior year's audit.

A retrospective study assessed 244 patients admitted with acute pancreatitis. Compliance with NICE Guidelines (NG104) was a focal point. Data collection included patient demographics, causes of acute pancreatitis, referrals to specialized programs, mortality rates, and adherence to recommended guidelines.

Of the 244 patients, 146 were male and 98 females. Biliary pathology and alcohol consumption were predominant causes. Notably, 18 patients were referred to the Remote Surveillance Program for Necrotizing Pancreatitis. Six patients (2.4%) succumbed to complications such as ARDS, AKI, necrotic pancreatitis, and bleeding. The audit revealed a mortality rate of 2.4%, showing improvement compared to the previous year's 2.5%.

The study demonstrated successful adherence to NICE guidelines, resulting in reduced morbidity and mortality rates (18%, 2.4%). Collaboration with the Freeman Hospital for referrals and multidisciplinary discussions played a pivotal role. Recommendations include continued adherence to guidelines, vigilance in reporting necrotic cases, and regular audits for ongoing quality improvement. The findings affirm the effectiveness of implemented measures and emphasize the importance of sustained adherence to protocols in managing acute pancreatitis at Cumberland Infirmary.